I don't think they ask us much besides acknowledging their existence and that we share the experience of having a vagina and menstruating. It is also possible that since we share biology, that experiences related to that also are similar. And they might have grow up with similar socialising than us until they were able to affirm their real identity.

In a way, they give us insight on what kind of things are completely unrelated to biology and what are just society expectations. I mean, when the very same person is treated differently depending on others perception of their gender, it is in plain sight that it is not about skill, capacity or anything biological, because all that remains the same.